19,75881 % | BVF Partners L.P. | 8.748.629 | 0 | 9.4.2025 |
9,71157 % | Tang Capital Management, LLC | 4.300.000 | 0 | 31.3.2025 |
9,53438 % | BML Capital Management LLC | 4.221.546 | 0 | 24.4.2025 |
9,48573 % | Morgan Stanley & Co. LLC | 4.200.007 | 10.759 | 31.3.2025 |
5,10879 % | Soleus Capital Management, L.P. | 2.262.026 | 0 | 23.4.2025 |
4,99129 % | Opaleye Management Inc. | 2.209.998 | 0 | 31.3.2025 |
3,78299 % | Pfizer Inc | 1.675.000 | 0 | 31.3.2025 |
2,37226 % | Altium Capital Management LP | 1.050.369 | -377.631 | 31.3.2025 |
1,77158 % | Berger (Franklin Milan) | 784.404 | 0 | 8.1.2025 |
1,57704 % | BofA Global Research (US) | 698.268 | -114.042 | 31.3.2025 |
1,28575 % | Aldebaran Capital, LLC | 569.294 | 171.771 | 31.3.2025 |
1,25397 % | Two Sigma Investments, LP | 555.220 | 245.473 | 31.3.2025 |
1,12925 % | Aguja Capital GmbH | 500.000 | 0 | 31.1.2025 |
0,53165 % | BNP Paribas Securities Corp. North America | 235.401 | 70.806 | 31.3.2025 |
0,48514 % | Medical Strategy GmbH | 214.804 | -54.500 | 30.11.2024 |
0,41479 % | DLD Asset Management, LP | 183.658 | 183.658 | 31.3.2025 |
0,37232 % | J.P. Morgan Securities LLC | 164.854 | 164.854 | 31.3.2025 |
0,24937 % | Deuterium Capital Management, LLC | 110.412 | 110.412 | 31.3.2025 |
0,22481 % | Morgan Stanley Smith Barney LLC | 99.540 | 93.140 | 31.3.2025 |
0,18548 % | Citadel Advisors LLC | 82.123 | -76.918 | 31.3.2025 |
0,14853 % | Parkinson (David Ross M.D.) | 65.765 | 0 | 8.1.2025 |
0,12468 % | Magnus Financial Group LLC | 55.206 | 0 | 31.3.2025 |
0,11676 % | Glickman (Richard M) | 51.700 | -8.460 | 8.1.2025 |
0,10473 % | American Century Investment Management, Inc. | 46.373 | 0 | 31.3.2025 |
0,10429 % | Avantis Investors | 46.176 | 26.132 | 31.3.2024 |
0,07587 % | Wood (David Sidney) | 33.593 | 250 | 8.1.2025 |
0,07159 % | Lepercq de Neuflize Asset Management, LLC | 31.700 | 1.500 | 31.3.2025 |
0,06821 % | Lepercq Corporation Management Ltd | 30.200 | 30.200 | 31.12.2024 |
0,06776 % | Requadt (Scott) | 30.002 | 0 | 8.1.2025 |
0,06066 % | Geode Capital Management, L.L.C. | 26.858 | 0 | 31.3.2025 |
0,05563 % | Shay Capital LLC | 24.631 | 24.631 | 31.3.2025 |
0,05332 % | UBS Financial Services, Inc. | 23.608 | -72.006 | 31.3.2025 |
0,05159 % | Schonfeld Strategic Advisors LLC | 22.843 | -26.000 | 31.3.2025 |
0,05156 % | XTX Markets LLC | 22.829 | -14.697 | 31.3.2025 |
0,04770 % | Group One Trading, L.P. | 21.118 | -15.230 | 31.3.2025 |
0,03636 % | Tucker Asset Management LLC | 16.097 | 16.097 | 31.3.2024 |
0,03214 % | Martin (John Alexander) | 14.229 | 0 | 8.1.2025 |
0,03188 % | Cubist Systematic Strategies, LLC | 14.115 | -12.172 | 31.3.2025 |
0,01756 % | Virsik (Peter) | 7.776 | 0 | 8.1.2025 |
0,01355 % | Osaic Holdings, Inc. | 6.000 | 0 | 31.3.2025 |
0,01316 % | BlackRock Financial Management, Inc. | 5.826 | 0 | 31.3.2025 |
0,01157 % | Cesano (Alessandra) | 5.124 | 0 | 8.1.2025 |
0,00915 % | Desjardins Securities Inc. | 4.050 | 0 | 31.3.2025 |
0,00833 % | Truvestments Capital LLC | 3.688 | -253 | 31.3.2025 |
0,00651 % | Thorell (Marella) | 2.881 | 0 | 8.1.2025 |
0,00565 % | CIBC Private Wealth Management | 2.500 | 0 | 31.3.2025 |
0,00282 % | BlackRock Institutional Trust Company, N.A. | 1.248 | 0 | 31.3.2025 |
0,00203 % | TD Waterhouse Canada, Inc. | 900 | 0 | 31.3.2025 |
0,00152 % | RBC Dominion Securities, Inc. | 675 | -100 | 31.3.2025 |
0,00136 % | Laurel Wealth Advisors, LLC | 600 | 0 | 31.3.2025 |
0,00080 % | Barclays Bank PLC | 355 | 0 | 31.3.2025 |
0,00050 % | Morgan Stanley Canada Limited | 221 | 0 | 31.3.2025 |
0,00032 % | RBC Capital Markets Wealth Management | 142 | -1 | 31.3.2025 |
0,00005 % | J.P. Morgan Securities plc | 21 | 0 | 31.3.2025 |
0 % | Squarepoint Capital LLP | 0 | -14.525 | 31.3.2025 |
0 % | Simplex Trading, LLC | 0 | -5.162 | 31.12.2024 |
0 % | Blackstone Alternative Investment Advisors LLC | 0 | -800 | 31.12.2023 |
0 % | Hunting Hill Global Capital, LLC | 0 | -10.000 | 31.12.2023 |
0 % | Rock Springs Capital Management LP | 0 | -677.005 | 31.12.2024 |
0 % | Rhenman & Partners Asset Management AB | 0 | -804.649 | 31.12.2024 |
0 % | RTW Investments L.P. | 0 | -1.113.002 | 31.3.2025 |
0 % | Jane Street Capital, L.L.C. | 0 | -45.810 | 31.3.2025 |
0 % | Susquehanna International Group, LLP | 0 | -17.704 | 31.3.2025 |
0 % | PFM Health Sciences, LP | 0 | -2.742.936 | 31.12.2024 |
0 % | Connective Capital Management, LLC | 0 | -84.578 | 31.12.2023 |
0 % | Prelude Capital Management, LLC | 0 | -25.000 | 31.3.2025 |
0 % | Tower Research Capital LLC | 0 | -27 | 30.9.2023 |
0 % | Northern Trust Global Investments | 0 | -4.661 | 30.9.2023 |
0 % | TD Securities, Inc. | 0 | -48 | 30.9.2024 |
0 % | RBC Capital Partners | 0 | -537 | 30.9.2024 |
0 % | Bellevue Asset Management AG | 0 | -7.879.583 | 1.11.2024 |
0 % | Adage Capital Management, L.P. | 0 | -1.474.165 | 31.12.2024 |
0 % | Marshall Wace LLP | 0 | -181.217 | 31.3.2025 |
0 % | Millennium Management LLC | 0 | -14.052 | 30.6.2024 |
0 % | Renaissance Technologies LLC | 0 | -24.234 | 31.3.2024 |
0 % | OrbiMed Advisors, LLC | 0 | -842.366 | 31.12.2023 |
0 % | D. E. Shaw & Co., L.P. | 0 | -62.955 | 31.12.2024 |
0 % | Acadian Asset Management LLC | 0 | -15.687 | 31.3.2025 |
0 % | Driehaus Capital Management, LLC | 0 | -28.300 | 30.9.2023 |
0 % | Janus Henderson Investors | 0 | -1.006.202 | 30.9.2024 |
0 % | CIBC World Markets Inc. | 0 | -73.587 | 31.12.2024 |
0 % | State Street Global Advisors (US) | 0 | -24.414 | 30.9.2023 |
0 % | Northern Trust Investments, Inc. | 0 | -7.828 | 30.9.2023 |
0 % | Kennedy Capital Management LLC | 0 | -41.092 | 31.12.2024 |
0 % | Parametric Portfolio Associates LLC | 0 | -194 | 31.12.2024 |
0 % | 49 Financial | 0 | -11.172 | 31.3.2025 |
0 % | Entrypoint Capital LLC | 0 | -4.420 | 30.6.2024 |
0 % | Privium Fund Management (UK) Ltd | 0 | -20.032 | 31.3.2024 |
0 % | GTS Securities LLC | 0 | -16.700 | 31.3.2025 |
0 % | Vazirani Asset Management LLC | 0 | -50.000 | 31.3.2025 |
0 % | Parkman Healthcare Partners LLC | 0 | -345.902 | 31.12.2024 |
0 % | FNY Investment Advisers LLC | 0 | -25.000 | 31.3.2025 |