8,94377 % | RTW Investments L.P. | 3.834.794 | 0 | 31.3.2025 |
7,47789 % | RA Capital Management, LP | 3.206.271 | 3.206.271 | 31.3.2025 |
6,15719 % | UBS Asset Management (Switzerland) | 2.640.000 | 1.283.916 | 31.3.2025 |
5,37129 % | Menora Mivtachim Insurance Ltd. | 2.303.031 | 0 | 31.3.2025 |
5,02127 % | Vestal Point Capital, LP | 2.152.957 | 522.957 | 31.3.2025 |
4,99749 % | BlackRock Institutional Trust Company, N.A. | 2.142.757 | -50.009 | 31.3.2025 |
4,07947 % | TD Securities, Inc. | 1.749.142 | 0 | 31.3.2025 |
4,01272 % | UBS Asset Management (Americas) LLC | 1.720.524 | 1.720.524 | 31.3.2025 |
3,53643 % | Acorn Capital Advisors, LLC | 1.516.303 | 0 | 31.3.2025 |
3,46381 % | Pontifax Venture Capital | 1.485.168 | -1 | 14.3.2024 |
3,22123 % | SilverArc Capital Management, LLC | 1.381.158 | 260.685 | 31.3.2025 |
3,19361 % | Arkin Communication, Ltd. | 1.369.315 | 0 | 22.2.2024 |
3,17981 % | Nantahala Capital Management, LLC | 1.363.399 | -8.239 | 31.3.2025 |
3,07860 % | UBS Asset Management Switzerland AG | 1.320.000 | 0 | 31.1.2025 |
2,97831 % | Adage Capital Management, L.P. | 1.277.000 | -1.651.086 | 31.3.2025 |
2,48136 % | UBS Switzerland AG | 1.063.924 | 220.524 | 31.3.2025 |
2,21566 % | Rosalind Advisors, Inc. | 950.000 | 80.000 | 31.3.2025 |
1,90080 % | Jefferies LLC | 815.000 | -150.929 | 31.3.2025 |
1,85418 % | State Street Global Advisors (US) | 795.012 | -13.041 | 31.3.2025 |
1,83426 % | Migdal Insurance and Financial Holdings Ltd | 786.472 | 100.000 | 31.3.2025 |
1,49251 % | Medical Strategy GmbH | 639.941 | 52.263 | 30.11.2024 |
1,45347 % | Morgan Stanley Investment Management Inc. (US) | 623.200 | -11 | 31.3.2025 |
1,15589 % | Wildcat Capital Management, LLC | 495.606 | 0 | 31.3.2025 |
1,14868 % | Dafna Capital Management, LLC | 492.515 | 0 | 31.3.2025 |
1,10393 % | Geode Capital Management, L.L.C. | 473.330 | 11.428 | 31.3.2025 |
0,98802 % | Superstring Capital Management LP | 423.632 | 122.426 | 31.3.2025 |
0,98791 % | Millennium Management LLC | 423.585 | -222.200 | 31.3.2025 |
0,95765 % | Hudson Bay Capital Management LP | 410.607 | 177.285 | 31.3.2025 |
0,95318 % | Belldegrun (Arie S) | 408.693 | 0 | 31.3.2025 |
0,93421 % | Atom Investors LP | 400.560 | 254.828 | 31.3.2025 |
0,91694 % | Parkman Healthcare Partners LLC | 393.153 | 23.292 | 31.3.2025 |
0,87223 % | Harel Insurance Investments and Financial Services Ltd | 373.982 | -89.285 | 31.3.2025 |
0,82094 % | T. Rowe Price Associates, Inc. | 351.992 | -26.196 | 31.3.2025 |
0,81499 % | J.P. Morgan Securities LLC | 349.440 | 349.440 | 31.3.2025 |
0,77758 % | Stonepine Capital Management, LLC | 333.400 | 9.076 | 31.3.2025 |
0,76193 % | Barrett (Elizabeth A) | 326.691 | -250 | 31.3.2025 |
0,71454 % | Woodline Partners LP | 306.371 | 729 | 31.3.2025 |
0,70760 % | Schroder Investment Management Ltd. (SIM) | 303.397 | 303.397 | 31.3.2025 |
0,62500 % | Northern Trust Investments, Inc. | 267.980 | -26.800 | 31.3.2025 |
0,59657 % | Rice Hall James & Associates, LLC | 255.791 | -8.240 | 31.3.2025 |
0,58407 % | The Vanguard Group, Inc. | 250.429 | -40.334 | 31.3.2025 |
0,57902 % | Goldman Sachs & Company, Inc. | 248.265 | -38.302 | 31.3.2025 |
0,55043 % | Point72 Asset Management, L.P. | 236.006 | -81.108 | 31.3.2025 |
0,46923 % | Morgan Stanley & Co. LLC | 201.189 | 77.914 | 31.3.2025 |
0,45927 % | Wells Fargo Advisors | 196.920 | -5.496 | 31.3.2025 |
0,45900 % | BofA Global Research (US) | 196.802 | 124.330 | 31.3.2025 |
0,44238 % | Citadel Advisors LLC | 189.677 | -39.108 | 31.3.2025 |
0,43331 % | ARK Investment Management LLC | 185.790 | 45.642 | 31.3.2025 |
0,37903 % | SG Americas Securities, L.L.C. | 162.514 | 142.245 | 31.3.2025 |
0,34536 % | Wellington Management Company, LLP | 148.078 | 1.125 | 31.3.2025 |
0,33513 % | Schoenberg (Mark) | 143.693 | 3.449 | 31.1.2025 |
0,30888 % | Epoch Investment Partners, Inc. | 132.439 | 6.751 | 31.3.2025 |
0,26603 % | AQR Capital Management, LLC | 114.066 | 88.577 | 31.3.2025 |
0,25460 % | UBS Financial Services, Inc. | 109.164 | 29.866 | 31.3.2025 |
0,25100 % | Privium Fund Management BV | 107.622 | 79.931 | 31.3.2025 |
0,23718 % | BlackRock Investment Management, LLC | 101.695 | -410 | 31.3.2025 |
0,22157 % | Cantor Fitzgerald, L.P | 95.000 | -265.000 | 31.3.2025 |
0,21818 % | Charles Schwab Investment Management, Inc. | 93.547 | 30 | 31.3.2025 |
0,21661 % | PanAgora Asset Management Inc. | 92.877 | 92.877 | 31.3.2025 |
0,21463 % | Susquehanna International Group, LLP | 92.025 | 51.892 | 31.3.2025 |
0,21269 % | Nuveen LLC | 91.194 | 0 | 31.3.2025 |
0,21130 % | Renaissance Technologies LLC | 90.600 | -47.600 | 31.3.2025 |
0,20369 % | BlackRock Financial Management, Inc. | 87.334 | -7.536 | 31.3.2025 |
0,19010 % | De Lisle Partners LLP | 81.510 | 0 | 31.3.2025 |
0,17980 % | Valu-Trac Investment Management Ltd. | 77.093 | -1.234 | 31.3.2024 |
0,17777 % | Diadema Partners LP | 76.220 | 26.220 | 31.3.2025 |
0,17621 % | Annandale Capital, LLC | 75.552 | 0 | 31.3.2025 |
0,17352 % | WesBanco Bank, Inc. | 74.400 | 0 | 31.3.2025 |
0,17190 % | Oak Ridge Investments, LLC | 73.704 | 12.539 | 31.3.2025 |
0,16423 % | AllianceBernstein L.P. | 70.417 | -128.842 | 31.3.2025 |
0,16277 % | Schonfeld Strategic Advisors LLC | 69.789 | 1.689 | 31.3.2025 |
0,15617 % | BlackRock Advisors (UK) Limited | 66.959 | -924 | 31.5.2025 |
0,14649 % | Susquehanna Fundamental Investments, LLC | 62.809 | 43.268 | 31.3.2025 |
0,14383 % | BlackRock Asset Management Ireland Limited | 61.669 | -1.502 | 31.3.2025 |
0,13556 % | BNY Mellon Asset Management | 58.125 | 627 | 31.3.2025 |
0,12470 % | Rhumbline Advisers Ltd. Partnership | 53.466 | 2.196 | 31.3.2025 |
0,12454 % | TD Asset Management Inc. | 53.400 | 0 | 31.3.2025 |
0,11936 % | Jane Street Capital, L.L.C. | 51.177 | 24.839 | 31.3.2025 |
0,10516 % | Kim (Dong) | 45.087 | 24.668 | 31.3.2025 |
0,10388 % | Barclays Bank PLC | 44.540 | -24.785 | 31.3.2025 |
0,08905 % | Manulife Investment Management (North America) Limited | 38.182 | 696 | 31.3.2025 |
0,08629 % | Coastal Bridge Advisors, LLC | 37.000 | -2.000 | 31.3.2025 |
0,08459 % | Fox Run Management, L.L.C | 36.271 | 36.271 | 31.3.2025 |
0,08428 % | Meitav Dash Investments Ltd. | 36.138 | 0 | 31.3.2025 |
0,08412 % | Goldman Sachs Asset Management, L.P. | 36.069 | 5.114 | 31.3.2025 |
0,08248 % | Mellon Investments Corporation | 35.365 | -1.134 | 31.3.2025 |
0,07873 % | Columbia Threadneedle Investments (US) | 33.758 | -15.395 | 31.3.2025 |
0,07641 % | Squarepoint Capital LLP | 32.764 | -17.430 | 31.3.2025 |
0,07641 % | Alps Advisors, Inc. | 32.762 | -1.359 | 31.3.2025 |
0,07583 % | Smith (Jason Drew) | 32.514 | 0 | 31.3.2025 |
0,07298 % | Kovitz Investment Group Partners, LLC | 31.291 | 0 | 31.3.2025 |
0,06932 % | Aperio Group, LLC | 29.724 | 22.099 | 31.3.2025 |
0,06922 % | Tidal Investments LLC | 29.679 | -847 | 31.3.2025 |
0,06828 % | Citi Investment Research (US) | 29.277 | -8.733 | 31.3.2025 |
0,06184 % | DWS Investments UK Limited | 26.514 | -4.081 | 31.3.2025 |
0,06149 % | INTECH Investment Management LLC | 26.363 | 2.374 | 31.3.2025 |
0,06056 % | XTX Markets LLC | 25.967 | 7.326 | 31.3.2025 |
0,05912 % | Group One Trading, L.P. | 25.350 | 23.961 | 31.3.2025 |
0,05878 % | Morgan Stanley Smith Barney LLC | 25.204 | 20.554 | 31.3.2025 |
0,05831 % | Kynam Capital Management LP | 25.000 | 25.000 | 31.3.2025 |